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1

Gq/11 and Gi/o activation profiles in CHO cells expressing human muscarinic acetylcholine receptors: dependence on agonist as well as receptor-subtype

Elizabeth C Akam, R A John Challiss, Stefan R Nahorski

Journal:

British Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 208 KB

english, 2001

2

Insulin sensitivity of rates of glycolysis and glycogen synthesis in soleus, stripped soleus, epitrochlearis, and hemi-diaphragm muscles isolated from sedentary rats

R. A. J. Challiss, J. Espinal, E. A. Newsholme

Journal:

Bioscience Reports

Year:

1983

Language:

english

File:

PDF, 376 KB

english, 1983

3

Expression of Insect Olfactory Receptors for Biosensing on SAW Sensors

Melissa D. Jordan, R.A. John Challiss

Journal:

Procedia Computer Science

Year:

2011

Language:

english

File:

PDF, 210 KB

english, 2011

4

Lithium and the phosphoinositide cycle: an example of uncompetitive inhibition and its pharmacological consequences

Stefan R. Nahorski, C. Ian Ragan, R.A.John Challiss

Journal:

Trends in Pharmacological Sciences

Year:

1991

Language:

english

File:

PDF, 1.07 MB

english, 1991

5

Regulation of neuronal plasticity and fear by a dynamic change in PAR1–G protein coupling in the amygdala

Bourgognon, J-M, Schiavon, E, Salah-Uddin, H, Skrzypiec, A E, Attwood, B K, Shah, R S, Patel, S G, Mucha, M, John Challiss, R A, Forsythe, I D, Pawlak, R

Journal:

Molecular Psychiatry

Year:

2013

Language:

english

File:

PDF, 1.56 MB

english, 2013

6

[Methods in Molecular Biology] Receptor Signal Transduction Protocols Volume 746 ||

Willars, Gary B., Challiss, R.A. John

Year:

2011

Language:

english

File:

PDF, 8.74 MB

english, 2011

7

Substrate cycles: their role in improving sensitivity in metabolic control

Newsholme, E.A., Challiss, R.A.J., Crabtree, B.

Journal:

Trends in Biochemical Sciences

Year:

1984

Language:

english

File:

PDF, 485 KB

english, 1984

8

[IEEE 2009 IEEE Sensors - Christchurch, New Zealand (2009.10.25-2009.10.28)] 2009 IEEE Sensors - Biomimetic insect infochemical communication system

Cole, M., Gardner, J.W., Racz, Z., Pathak, S., Pearce, T.C., Challiss, J., Markovic, D., Guerrero, A., Munoz, L., Carot, G., Hansson, B.S., Olsson, S., Kubler, L., Gardeniers, J. G. E., Dimov, N., Bul

Year:

2009

Language:

english

File:

PDF, 636 KB

english, 2009

9

Biosynthetic infochemical communication

Olsson, S B, Challiss, R A J, Cole, M, Gardeniers, J G E, Gardner, J W, Guerrero, A, Hansson, B S, Pearce, T C

Journal:

Bioinspiration & Biomimetics

Year:

2015

Language:

english

File:

PDF, 2.17 MB

english, 2015

10

Spirophostins: Conformationally Restricted Analogues of Adenophostin A

Martin de Kort, Anouk D. Regenbogen, A. Rob P. M. Valentijn, R. A. John Challiss, Yoriko Iwata, Shuichi Miyamoto, Gijs A. van der Marel, Jacques H. van Boom

Journal:

Chemistry - A European Journal

Year:

2000

Language:

english

File:

PDF, 278 KB

english, 2000

11

Effects of adenosine deaminase on the sensitivity of glucose transport, glycolysis and glycogen systhesis to insulin in muscles of the rat

Brendan Leighton, Fred J. Lozeman, Ioannis G. Vlachonikolis, R.A.John Challiss, Julie A. Pitcher, Eric A. Newsholme

Journal:

International Journal of Biochemistry

Year:

1988

Language:

english

File:

PDF, 459 KB

english, 1988

12

One-dimensional rotating-frame imaging of phosphorus metabolites in vivo

Martin J Blackledge, David J Hayes, R.A.John Challiss, George K Radda

Journal:

Journal of Magnetic Resonance (1969)

Year:

1969

Language:

english

File:

PDF, 446 KB

english, 1969

13

Synthesis and Biological Evaluation of Cyclophostin: A 5′,6″-Tethered Analog of Adenophostin A

Martin de Kort, Anouk D. Regenbogen, Herman S. Overkleeft, R.A. John Challiss, Yoriko Iwata, Shuichi Miyamoto, Gijs A. van der Marel, Jacques H. van Boom

Journal:

Year:

2000

Language:

english

File:

PDF, 266 KB

english, 2000

14

Characterization of an N-terminal secreted domain of the type-1 human metabotropic glutamate receptor produced by a mammalian cell line

Julie V. Selkirk, R. A. John Challiss, Andrew Rhodes, R. A. Jeffrey McIlhinney

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 245 KB

english, 2002

15

The effects of insulin on transport and metabolism of glucose in skeletal muscle from hyperthyroid and hypothyroid rats

G. DIMITRIADIS, M. PARRY-BILLINGS, S. BEVAN, B. LEIGHTON, U. KRAUSE, T. PIVA, K. TEGOS, R. A. J. CHALLISS, G. WEGENER, E. A. NEWSHOLME

Journal:

European Journal of Clinical Investigation

Year:

1997

Language:

english

File:

PDF, 669 KB

english, 1997

16

Differential Effects of Lithium on Muscarinic Cholinoceptor-Stimulated CMP-Phosphatidate Accumulation in Cerebellar Granule Cells, CHO-M3 Cells, and SH-SY5Y Neuroblastoma Cells

David W. Gray, R. A. John Challiss, Stefan R. Nahorski

Journal:

Journal of Neurochemistry

Year:

1994

Language:

english

File:

PDF, 757 KB

english, 1994

17

Chronic Activation of Muscarinic and Metabotropic Glutamate Receptors Down-Regulates Type I Inositol 1,4,5-Trisphosphate Receptor Expression in Cerebellar Granule Cells

Peter B. Simpson, R. A. John Challiss, Stefan R. Nahorski

Journal:

Journal of Neurochemistry

Year:

1994

Language:

english

File:

PDF, 421 KB

english, 1994

18

Muscarinic Cholinoceptor-Stimulated Synthesis and Degradation of Inositol 1,4,5-Trisphosphate in the Rat Cerebellar Granule Cell

David W. Gray, Emma M. Whitham, R. A. John Challiss, Stefan R. Nahorski

Journal:

Journal of Neurochemistry

Year:

1995

Language:

english

File:

PDF, 875 KB

english, 1995

19

Agonist-Evoked Ca2+ Mobilization from Stores Expressing Inositol 1,4,5-Trisphosphate Receptors and Ryanodine Receptors in Cerebellar Granule Neurones

Peter B. Simpson, Stefan R. Nahorski, R. A. John Challiss

Journal:

Journal of Neurochemistry

Year:

1996

Language:

english

File:

PDF, 1.05 MB

english, 1996

20

Regulatory Properties of the Mammalian Adenylyl Cyclases : by Zhengui Xia and Daniel R. Storm. R. G. Landes Co., Austin, Texas, 1996, ISBN 0-412-12251-0, 175 pp., $89.95.

R. A. John Challiss

Journal:

Journal of Neurochemistry

Year:

1997

Language:

english

File:

PDF, 97 KB

english, 1997

21

Effects of Human Type 1α Metabotropic Glutamate Receptor Expression Level on Phosphoinositide and Ca2+ Signalling in an Inducible Cell Expression System

E. Hermans, K. W. Young, R. A. J. Challiss, S. R. Nahorski

Journal:

Journal of Neurochemistry

Year:

1998

Language:

english

File:

PDF, 467 KB

english, 1998

22

Enhanced inducible mGlu1α receptor expression in Chinese hamster ovary cells

Mark S. Nash, Julie V. Selkirk, Caroline E. Gaymer, R. A. John Challiss, Stefan R. Nahorski

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 382 KB

english, 2001

23

Group-I metabotropic glutamate receptors, mGlu1a and mGlu5a, couple to extracellular signal-regulated kinase (ERK) activation via distinct, but overlapping, signalling pathways

Sukhwinder Thandi, Jonathan L. Blank, R. A. John Challiss

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 790 KB

english, 2002

24

Effects of dipyridamole on adenosine concentration, insulin sensitivity and glucose utilisation in soleus muscle of the rat

Fred J. Lozeman, R. A. John Challiss, Brendan Leighton, Eric A. Newsholme

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1987

Language:

english

File:

PDF, 707 KB

english, 1987

25

Alternative splicing of G protein-coupled receptors: physiology and pathophysiology

Danijela Markovic, R. A. John Challiss

Journal:

Cellular and Molecular Life Sciences

Year:

2009

Language:

english

File:

PDF, 416 KB

english, 2009

26

Divalent Cation Entry in Cultured Rat Cerebellar Granule Cells Measured Using Mn2+ Quench of Fura 2 Fluorescence

P. B. Simpson, R. A. J. Challiss, S. R. Nahorski

Journal:

European Journal of Neuroscience

Year:

1995

Language:

english

File:

PDF, 1.06 MB

english, 1995

27

Lithium Reduqes the Accumulation or Inositol Polyphosphate Second Messengers Following Cholinergic Stimulation of Cerebral Cortex Slices

Eleanor D. Kennedy, R. A. John Challiss, Stefan R. Nahorski

Journal:

Journal of Neurochemistry

Year:

1989

Language:

english

File:

PDF, 412 KB

english, 1989

28

Neurotransmitter and Depolarization-Stimulated Accumulation of Inositol 1,3,4,5-Tetrakisphosphate Mass in Rat Cerebral Cortex Slices

R. A. John Challiss, Stefan R. Nahorski

Journal:

Journal of Neurochemistry

Year:

1990

Language:

english

File:

PDF, 439 KB

english, 1990

29

Changes in Inositol 1,4,5-Trisphosphate and Inositol 1,3,4,5-Tetrakisphosphate Mass Accumulations in Cultured Adrenal Chromaffin Cells in Response to Bradykinin and Histamine

R. A. John Challiss, J. Alison Jones, P. Jane Owen, Michael R. Boarder

Journal:

Journal of Neurochemistry

Year:

1991

Language:

english

File:

PDF, 417 KB

english, 1991

30

Depolarization and Agonist-Stimulated Changes in Inositol 1,4,5-Trisphosphate and Inositol 1,3,4,5-Tetrakisphosphate Mass Accumulation in Rat Cerebral Cortex

R. A. John Challiss, Stefan R. Nahorski

Journal:

Journal of Neurochemistry

Year:

1991

Language:

english

File:

PDF, 1.04 MB

english, 1991

31

Involvement of Intracellular Stores in the Ca2+ Responses to N-Methyl-D-Aspartate and Depolarization in Cerebellar Granule Cells

Peter B. Simpson, R. A. John Challiss, Stefan R. Nahorski

Journal:

Journal of Neurochemistry

Year:

1993

Language:

english

File:

PDF, 430 KB

english, 1993

32

Comparative Effects of Lithium on the Phosphoinositide Cycle in Rat Cerebral Cortex, Hippocampus, and Striatum

Stephen Jenkinson, Neela Patel, Stefan R. Nahorski, R. A. John Challiss

Journal:

Journal of Neurochemistry

Year:

1993

Language:

english

File:

PDF, 948 KB

english, 1993

33

NMDA-receptor regulation of muscarinic-receptor stimulated inositol 1,4,5-trisphosphate production and protein kinase C activation in single cerebellar granule neurons

Kenneth W. Young, M. Asier Garro, R. A. John Challiss, Stefan R. Nahorski

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 472 KB

english, 2004

34

Group I metabotropic glutamate receptors, mGlu1a and mGlu5a, couple to cyclic AMP response element binding protein (CREB) through a common Ca2+- and protein kinase C-dependent pathway

Helen K. Warwick, Stefan R. Nahorski, R. A. John Challiss

Journal:

Journal of Neurochemistry

Year:

2005

Language:

english

File:

PDF, 468 KB

english, 2005

35

The regulation of M1 muscarinic acetylcholine receptor desensitization by synaptic activity in cultured hippocampal neurons

Jonathon M. Willets, Carl P. Nelson, Stefan R. Nahorski, R. A. John Challiss

Journal:

Journal of Neurochemistry

Year:

2007

Language:

english

File:

PDF, 519 KB

english, 2007

36

Temporal profiling of changes in phosphatidylinositol 4,5-bisphosphate, inositol 1,4,5-trisphosphate and diacylglycerol allows comprehensive analysis of phospholipase C-initiated signalling in single neurons

Carl P. Nelson, Stefan R. Nahorski, R. A. John Challiss

Journal:

Journal of Neurochemistry

Year:

2008

Language:

english

File:

PDF, 843 KB

english, 2008

37

Arrestins differentially regulate histamine- and oxytocin-evoked phospholipase C and mitogen-activated protein kinase signalling in myometrial cells

Paul J Brighton, Shashi Rana, RA John Challiss, Justin C Konje, Jonathon M Willets

Journal:

British Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.52 MB

english, 2011

38

Defining protein kinase/phosphatase isoenzymic regulation of mGlu5 receptor-stimulated phospholipase C and Ca2+ responses in astrocytes

SJ Bradley, RAJ Challiss

Journal:

British Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 2.27 MB

english, 2011

39

10.1038/35096643

Nash, Mark S., Young, Kenneth W., John Challiss, R. A., Nahorski, Stefan R.

Journal:

Year:

2001

Language:

english

File:

PDF, 157 KB

english, 2001

40

Pharmacological characterization of type 1α metabotropic glutamate receptor-stimulated [35S]-GTPγS binding

Elizabeth C Akam, Alan M Carruthers, Stefan R Nahorski, R A John Challiss

Journal:

British Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 380 KB

english, 1997

41

Regulation of brain capillary endothelial cells by P2Y receptors coupled to Ca2+, phospholipase C and mitogen-activated protein kinase

Jennifer L. Albert, John P. Boyle, Jonathan A. Roberts, R. A. John Challiss, Sharon E. Gubby, Michael R. Boarder

Journal:

British Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 333 KB

english, 1997

42

Regulation of phosphoinositide turnover in neonatal rat cerebral cortex by group I- and II- selective metabotropic glutamate receptor agonists

Rajendra Mistry, Nicki Golding, R A. John Challiss

Journal:

British Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 388 KB

english, 1998

43

Modulation of spasmogen-stimulated Ins(1,4,5)P3 generation and functional responses by selective inhibitors of types 3 and 4 phosphodiesterase in airways smooth muscle

R A John Challiss, David Adams, Rajendra Mistry, C David Nicholson

Journal:

British Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 372 KB

english, 1998

44

Characterization of an atypical muscarinic cholinoceptor mediating contraction of the guinea-pig isolated uterus

Donna K Boxall, Anthony P D W Ford, Agnes Choppin, Stefan R Nahorski, R A John Challiss, Richard M Eglen

Journal:

British Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 314 KB

english, 1998

45

Effects of varying the expression level of recombinant human mGlu1α receptors on the pharmacological properties of agonists and antagonists

Emmanuel Hermans, R A John Challiss, Stefan R Nahorski

Journal:

British Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 427 KB

english, 1999

46

Cannabinoid CB1 receptors fail to cause relaxation, but couple via Gi/Go to the inhibition of adenylyl cyclase in carotid artery smooth muscle

Michael Holland, R A John Challiss, Nicholas B Standen, John P Boyle

Journal:

British Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 253 KB

english, 1999

47

Evidence for cross-talk between M2 and M3 muscarinic acetylcholine receptors in the regulation of second messenger and extracellular signal-regulated kinase signalling pathways in Chinese hamster ovary cells

David C Hornigold, Rajendra Mistry, Pamela D Raymond, Jonathan L Blank, R A John Challiss

Journal:

British Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 250 KB

english, 2003

48

An investigation of whether agonist-selective receptor conformations occur with respect to M2 and M4 muscarinic acetylcholine receptor signalling via Gi/o and Gs proteins

Rajendra Mistry, Mark R Dowling, R A John Challiss

Journal:

British Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 230 KB

english, 2005

49

Compartmentalized signalling in neurons

Paola Pedarzani, Shamshad Cockcroft, R. A. John Challiss

Journal:

The Journal of Physiology

Year:

2007

Language:

english

File:

PDF, 178 KB

english, 2007

50

Structural aspects of M3 muscarinic acetylcholine receptor dimer formation and activation

Hu, J., Thor, D., Zhou, Y., Liu, T., Wang, Y., McMillin, S. M., Mistry, R., Challiss, R. A. J., Costanzi, S., Wess, J.

Journal:

The FASEB Journal

Year:

2012

Language:

english

File:

PDF, 555 KB

english, 2012